SCHEMBL7356245

SCHEMBL7356245

Oc1c2ccccc2cc2cc3c(cc12)CC=CC3

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.38
TRPM4 Q8TD43 1/20 0.38
CASP6 P55212 1/20 0.38
NQO2 P16083 1/20 0.37
LDHA P00338 1/20 0.37
NQO1 P15559 1/20 0.37
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX5 P09917 1/20 0.36
POLB P06746 1/20 0.36
GPR35 Q9HC97 1/20 0.36
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057640 0.80 PTPN22 (0.39) PTPN22TRPM4CASP6NQO2LDHA
SCHEMBL30226888 0.80 PTPN22 (0.39) PTPN22TRPM4CASP6NQO2LDHA
SCHEMBL11757019 0.78 PTPN22 (0.48) PTPN22TRPM4CASP6NQO2LDHA
SCHEMBL437148 0.78 PTPN22 (0.56) PTPN22TRPM4CASP6NQO2LDHA
SCHEMBL31320895 0.77 PTPN22 (0.46) PTPN22TRPM4CASP6NQO2LDHA
Methane SCHEMBL2327641 0.76 PTPN22 (0.54) PTPN22TRPM4CASP6NQO2LDHA
SCHEMBL29180044 0.76 PTPN22 (0.54) PTPN22TRPM4CASP6NQO2LDHA
Hydrogen Sulfide SCHEMBL27992660 0.76 PTPN22 (0.54) PTPN22TRPM4CASP6NQO2LDHA
Methane SCHEMBL155047 0.76 PTPN22 (0.54) PTPN22TRPM4CASP6NQO2LDHA
SCHEMBL11112969 0.75 TRPM4 (0.56) PTPN22TRPM4CASP6NQO2NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4031137-A Catalysts based on carbon supports and use in catalytic deoxidation process AMERICAN CYANAMID COMPANY (US) 1977-06-21 US claimed
US-4035260-A REDUCTIVE DEPOSITION OF PLATINUM ON CARBON SUPPORT AMERICAN CYANAMID COMPANY (US) 1977-07-12 US disclosed
US-4031137-A Catalysts based on carbon supports and use in catalytic deoxidation process AMERICAN CYANAMID COMPANY (US) 1977-06-21 US disclosed
US-3978000-A REDUCTION AMERICAN CYANAMID COMPANY (US) 1976-08-31 US disclosed
US-3019260-A Process for the catalytic reduction of 6-hydroxy hydronaphthacenes AMERICAN CYANAMID CO 1962-01-30 US disclosed