Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.57 |
| ▸ | PLG | P00747 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356254 | 1.00 | F2 (0.57) | F2PLGOPRM1OPRD1OPRK1 | |
| SCHEMBL6850997 | 1.00 | F2 (0.57) | F2PLGOPRM1OPRD1OPRK1 | |
| SCHEMBL6850981 | 1.00 | F2 (0.57) | F2PLGOPRM1OPRD1OPRK1 | |
| SCHEMBL27532662 | 1.00 | F2 (0.57) | F2PLGOPRM1OPRD1OPRK1 | |
| Acetic Acid SCHEMBL10728075 | 0.99 | F2 (0.56) | F2PLGOPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11285878 | 0.99 | F2 (0.56) | F2PLGOPRM1OPRD1OPRK1 | |
| Sulfuric Acid SCHEMBL7264620 | 0.97 | F2 (0.54) | F2PLGOPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL7304367 | 0.92 | OPRM1 (0.49) | F2PLGOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7296655 | 0.90 | F2 (0.59) | F2PLGOPRM1OPRK1F10 | |
| SCHEMBL7395037 | 0.90 | F2 (0.53) | F2PLGOPRM1OPRK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079261-A1 | TETRAHYDRO-AZEPINONE DERIVATIVES AS THROMBIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
| EP-0684830-A4 | INHIBITORS OF THROMBOSIS. | CORVAS INT INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0684830-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0627929-A4 | INHIBITORS OF THROMBOSIS. | CORVAS INT INC (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1995014788-A1 | BLOOD COAGULATION RETARDANTS AND DEVICES | UNIVERSITY OF WASHINGTON (US) | 1995-06-01 | — | — | WO | disclosed |
| EP-0627929-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-12-14 | — | — | EP | disclosed |
| WO-1994017817-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-08-18 | — | — | WO | disclosed |