Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296506 | 0.88 | GPR34 (0.73) | GPR34KMT2AMEN1 | |
| SCHEMBL10727176 | 0.88 | GPR34 (0.73) | GPR34KMT2AMEN1 | |
| SCHEMBL7970010 | 0.88 | GPR34 (0.73) | GPR34KMT2AMEN1 | |
| SCHEMBL21959107 | 0.85 | GPR34 (0.65) | GPR34KMT2APPARGMEN1PTPN2 | |
| SCHEMBL18228648 | 0.85 | GPR34 (0.65) | GPR34KMT2APPARGMEN1PTPN2 | |
| SCHEMBL10724456 | 0.84 | GPR34 (0.83) | GPR34KMT2AMEN1PTPN2PTPN1 | |
| SCHEMBL28965739 | 0.84 | GPR34 (0.69) | GPR34KMT2AMEN1HTTPKM | |
| SCHEMBL28965736 | 0.84 | GPR34 (0.69) | GPR34KMT2AMEN1HTTPKM | |
| SCHEMBL27154066 | 0.84 | GPR34 (0.83) | GPR34KMT2AMEN1PTPN2PTPN1 | |
| SCHEMBL21391859 | 0.82 | GPR34 (0.71) | GPR34KMT2AMEN1PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650785-A | ORAL ADMINISTRATION OF INSULIN | AJINOMOTO COMPANY INCOPORATED (JP) | 1987-03-17 | — | — | US | claimed |
| WO-1999048911-A1 | MONOBACTAM ENZYME INHIBITORS | NAEJA PHARMACEUTICAL INC. (GB) | 1999-09-30 | — | — | WO | disclosed |
| US-4670584-A | PHENYLALANINE DERIVATIVES FOR INSULIN AND OTHER DRUGS | AJINOMOTO COMPANY INCORPORATED (JP) | 1987-06-02 | — | — | US | disclosed |
| US-4650785-A | ORAL ADMINISTRATION OF INSULIN | AJINOMOTO COMPANY INCOPORATED (JP) | 1987-03-17 | — | — | US | disclosed |
| EP-0093551-A2 | Pharmaceutical composition | AJINOMOTO CO., INC. (JP) | 1983-11-09 | — | — | EP | disclosed |