Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285375 | 0.93 | HSP90AA1 (0.58) | ALDH1A1MAPTKMT2AMEN1HSP90AA1 | |
| SCHEMBL29182622 | 0.91 | HSP90AA1 (0.61) | ALDH1A1KMT2AMEN1HSP90AA1CES2 | |
| SCHEMBL3190449 | 0.91 | HSP90AA1 (0.61) | ALDH1A1KMT2AMEN1HSP90AA1CES2 | |
| SCHEMBL28459110 | 0.91 | HSP90AA1 (0.61) | ALDH1A1KMT2AMEN1HSP90AA1CES2 | |
| SCHEMBL12700294 | 0.91 | HSP90AA1 (0.61) | ALDH1A1KMT2AMEN1HSP90AA1CES2 | |
| SCHEMBL25330155 | 0.91 | HSP90AA1 (0.61) | ALDH1A1KMT2AMEN1HSP90AA1CES2 | |
| SCHEMBL29539510 | 0.91 | HSP90AA1 (0.61) | ALDH1A1KMT2AMEN1HSP90AA1CES2 | |
| SCHEMBL6274637 | 0.91 | HSP90AA1 (0.61) | ALDH1A1KMT2AMEN1HSP90AA1CES2 | |
| SCHEMBL14405350 | 0.91 | HSP90AA1 (0.61) | ALDH1A1KMT2AMEN1HSP90AA1CES2 | |
| SCHEMBL5147801 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005448-A2 | NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS | Du Pont Pharmaceuticals Company (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1999009000-A2 | NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-02-25 | — | — | WO | claimed |
| CN-114432301-B | Covalent inhibitor derivative and application thereof in treatment of viral infection | 北京大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-115814713-A | System and method for preparing adiponitrile from adipic acid | 中国石油化工股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4077289-A1 | 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE | Oxford Drug Design Limited (GB) | 2022-10-26 | — | — | EP | disclosed |
| CN-104245814-B | Rubber composition | 湛新德国有限公司 | 2016-11-09 | — | — | CN | disclosed |
| US-20150051185-A1 | Chemical Compounds 251 | ASTRAZENECA AB (SE) | 2015-02-19 | — | — | US | disclosed |
| CN-104245814-A | Rubber compositions | CYTEC SURFACE SPECIALTIES GERMANY GMBH | 2014-12-24 | — | — | CN | disclosed |
| CN-103282448-A | Non-aqueous dispersions comprising a nonlinear acrylic stabilizer | PPG IND OHIO INC | 2013-09-04 | — | — | CN | disclosed |
| CN-1168702-C | Movel acyl pseudodipeoptides, prepn method and pharmaceutical compsns. contg. same | OMҩҵ | 2004-09-29 | — | — | CN | disclosed |
| CN-1385469-A | Asphalt liquefying agent | CHENGDU ORGANIC CHEM INST (CN) | 2002-12-18 | — | — | CN | disclosed |
| CN-1306504-A | Movel acyl pseudodipeoptides, prepn method and pharmaceutical compsns. contg. same | OM PHARMA (CH) | 2001-08-01 | — | — | CN | disclosed |
| EP-1005448-A2 | NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS | Du Pont Pharmaceuticals Company (US) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999009000-A2 | NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051185-A1 | Chemical Compounds 251 | PIM1, PIM3, PIM2 | ALDH1A1 683/4885MAPT 3277/4885KDM4E 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.