Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352944 | 0.91 | ACE (0.51) | ACECMA1 | |
| SCHEMBL7352347 | 0.84 | CMA1 (0.47) | ACECMA1 | |
| SCHEMBL7349272 | 0.82 | CMA1 (0.66) | CMA1 | |
| SCHEMBL7357635 | 0.82 | CMA1 (0.66) | CMA1 | |
| SCHEMBL7349280 | 0.82 | CMA1 (0.66) | CMA1 | |
| SCHEMBL3692085 | 0.82 | ACE (0.77) | ACEACE2CMA1 | |
| SCHEMBL3692081 | 0.82 | ACE (0.77) | ACEACE2CMA1 | |
| SCHEMBL5900836 | 0.82 | ACE (0.77) | ACEACE2CMA1 | |
| SCHEMBL22409423 | 0.82 | ACE (0.77) | ACEACE2CMA1 | |
| SCHEMBL8378100 | 0.82 | ACE (0.77) | ACEACE2CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025574-A1 | INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE | PFIZER INC. (US) | 1993-12-23 | — | — | WO | disclosed |