SCHEMBL7358174

SCHEMBL7358174

CCC(=O)N[C@@H](CC(N)=O)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.51
CYP2C9 P11712 1/20 0.42
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
GRB2 P62993 2/20 0.32
BMP1 P13497 1/20 0.32
CA2 P00918 3/20 0.32
CA4 P22748 1/20 0.32
NOD1 Q9Y239 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 1/20 0.31
CA1 P00915 1/20 0.31
SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15811060 1.00 ECE1 (0.51) ECE1CYP2C9MEN1KMT2AITGB2
SCHEMBL7358176 1.00 ECE1 (0.51) ECE1CYP2C9MEN1KMT2AITGB2
SCHEMBL26385399 0.93 ECE1 (0.54) ECE1CYP2C9MEN1KMT2AGRB2
SCHEMBL26081534 0.88 CA2 (0.43) ECE1CYP2C9BMP1CA2CA4
SCHEMBL10076073 0.88 CA2 (0.43) ECE1CYP2C9BMP1CA2CA4
SCHEMBL27512389 0.88 CA2 (0.43) ECE1CYP2C9BMP1CA2CA4
SCHEMBL4182303 0.86 ECE1 (0.53) ECE1CYP2C9MEN1KMT2AITGB2
SCHEMBL4182306 0.86 ECE1 (0.53) ECE1CYP2C9MEN1KMT2AITGB2
SCHEMBL10076119 0.86 ECE1 (0.53) ECE1CYP2C9MEN1KMT2AITGB2
SCHEMBL31256913 0.83 CYP2C9 (0.45) ECE1CYP2C9MEN1KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1005448-A2 NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS Du Pont Pharmaceuticals Company (US) 2000-06-07 EP claimed
WO-1999009000-A2 NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS DU PONT PHARMACEUTICALS COMPANY (US) 1999-02-25 WO claimed
US-20230312857-A1 NANOPORE DEVICES INCLUDING BARRIERS USING POLYMERS WITH END GROUPS, AND METHODS OF MAKING THE SAME ILLUMINA CAMBRIDGE LIMITED (GB) 2023-10-05 US disclosed
EP-1005448-A2 NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS Du Pont Pharmaceuticals Company (US) 2000-06-07 EP disclosed
WO-1999009000-A2 NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS DU PONT PHARMACEUTICALS COMPANY (US) 1999-02-25 WO disclosed