Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL18979870 | 0.89 | TSHR (0.45) | TSHRCYP1A2CYP2C9HSD17B10KEAP1 | |
| SCHEMBL736098 | 0.88 | HDAC3 (0.52) | TSHRCYP1A2HSD17B10KEAP1FFAR1 | |
| SCHEMBL27608146 | 0.86 | MAPT (0.52) | TSHRHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL2932213 | 0.85 | MAPT (0.55) | TSHRHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL30661655 | 0.85 | MAPT (0.55) | TSHRHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL736113 | 0.85 | MAPT (0.55) | TSHRHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL1471746 | 0.85 | MAPT (0.55) | TSHRHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL9680709 | 0.83 | MAPT (0.45) | TSHRCYP1A2CYP2C9HSD17B10HDAC3 | |
| SCHEMBL10362176 | 0.82 | ALDH1A1 (0.48) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7130655 | 0.82 | CAPN1 (0.47) | TSHRNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615559-B1 | MODIFIED COMPLEMENT PROTEINS AND USES THEREOF | UNIV NEWCASTLE (GB) | 2025-06-18 | — | — | EP | claimed |
| CN-119816735-A | Methods and assays for secretory proteome activity analysis | 康巴乔有限公司 | 2025-04-11 | — | — | CN | claimed |
| US-20240376172-A1 | INTERLEUKIN 2 CHIMERIC CONSTRUCTS WITH TARGETING SPECIFICY TO INFLAMED TISSUES | ILTOO PHARMA (FR) | 2024-11-14 | — | — | US | claimed |
| CN-118829420-A | Multivesicular lipid nanoparticle-tolerant vaccine for inducing systemic immune tolerance in vivo | 卡尔马ABC有限责任公司 | 2024-10-22 | — | — | CN | claimed |
| US-20240012011-A1 | METHODS AND ASSAYS FOR SECRETOME ACTIVITY ANALYSIS | OXFORD FINANCE LLC | 2024-01-11 | — | — | US | claimed |
| CN-116036084-A | Application of stephanine in preparing medicine for treating coronavirus infection patient | 上海甘合商务信息咨询有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-115954111-A | Method for searching clinical value target and analytic action mechanism of cepharanthine for treating EBV (Epstein Barr Virus) related tumors | 杨江平 | 2023-04-11 | — | — | CN | claimed |
| CN-115916174-A | Compositions and methods for preventing stress-induced phobia, depression-like, and anxiety-like behaviors | 纽约市哥伦比亚大学理事会 | 2023-04-04 | — | — | CN | claimed |
| CN-115245804-A | Device and process for improving reaction rate of azolepropanoic acid | 甘肃联凯生物科技有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-115057829-A | Synthesis method of high-purity azolepropanoic acid | 甘肃联凯生物科技有限公司 | 2022-09-16 | — | — | CN | claimed |
| US-20090155243-A1 | NON-HUMAN MODEL OF AUTOIMMUNE DISEASE | THE CLEVELAND CLINIC FOUNDATION (US) | 2009-06-18 | — | — | US | claimed |
| EP-2049156-A2 | COMPOSITIONS AND METHODS FOR MACULAR DEGENERATION | The Cleveland Clinic Foundation (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008089485-A2 | CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-07-24 | — | — | WO | claimed |
| US-20080160505-A1 | DIAGNOSTIC METHODS FOR AGE RELATED MACULAR DEGENERATION | THE CLEVELAND CLINIC FOUNDATION | 2008-07-03 | — | — | US | claimed |
| US-7341839-B2 | Diagnostic methods for age related macular degeneration | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-03-11 | — | — | US | claimed |
| WO-2008013797-A2 | COMPOSITIONS AND METHODS FOR MACULAR DEGENERATION | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2007127151-A2 | NON-HUMAN MODEL OF AUTOIMMUNE DISEASE | THE CLEVELAND CLINIC FOUNDATION (US) | 2007-11-08 | — | — | WO | claimed |
| US-20070072241-A1 | diagnosing age-related macular degeneration comprising determining the level of anti-2-( omega -carboxyethyl) pyrrole (CEP) antibodies in a bodily fluid obtained from the test subject | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-03-29 | — | — | US | claimed |
| US-7172874-B2 | Diagnostic methods for age related macular degeneration | THE CLEVELAND CLINIC FOUNDATION (US) | 2007-02-06 | — | — | US | claimed |
| US-20040265924-A1 | Diagnostic methods for age related macular degeneration | THE CLEVELAND CLINIC FOUNDATION | 2004-12-30 | — | — | US | claimed |