Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 18/20 | 0.58 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354866 | 0.91 | CACNA1B (0.57) | CACNA1BCCR5LMNAGAARAB9A | |
| SCHEMBL7354496 | 0.88 | CACNA1B (0.54) | CACNA1BCCR5LMNAGAARAB9A | |
| SCHEMBL7349589 | 0.88 | CACNA1B (0.69) | CACNA1BCCR5LMNAGAARAB9A | |
| SCHEMBL7355987 | 0.85 | CACNA1B (0.55) | CACNA1BCCR5LMNAGAARAB9A | |
| SCHEMBL7967526 | 0.82 | CACNA1B (0.65) | CACNA1B | |
| SCHEMBL7045126 | 0.80 | CACNA1B (0.81) | CACNA1B | |
| SCHEMBL7045341 | 0.78 | CACNA1B (0.59) | CACNA1BCCR5LMNAGAARAB9A | |
| SCHEMBL7037966 | 0.78 | CACNA1B (0.59) | CACNA1BCCR5LMNAGAARAB9A | |
| SCHEMBL7037965 | 0.78 | CACNA1B (0.59) | CACNA1BCCR5LMNAGAARAB9A | |
| SCHEMBL7349612 | 0.78 | CACNA1B (0.67) | CACNA1BCCR5LMNAGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |