Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359002 | 1.00 | HRH3 (0.69) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL9752578 | 0.99 | HRH3 (0.67) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| SCHEMBL6801436 | 0.96 | HRH3 (0.71) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| SCHEMBL8938430 | 0.85 | HRH3 (0.69) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| SCHEMBL4806889 | 0.84 | HRH3 (0.66) | HRH3SIGMAR1MEN1KMT2A | |
| SCHEMBL7355512 | 0.84 | HRH3 (0.66) | HRH3SIGMAR1MEN1KMT2A | |
| SCHEMBL4806896 | 0.84 | HRH3 (0.66) | HRH3SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9668778 | 0.84 | HRH3 (0.67) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| SCHEMBL10669091 | 0.82 | HRH3 (1.00) | HRH3SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL17294993 | 0.81 | HRH3 (0.97) | HRH3SIGMAR1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889043-B1 | 5,11-DIHYDRODIBENZ b,e] 1,4]OXAZEPINE DERIVATIVES AND DRUG COMPOSITIONS CONTAING THE DERIVATIVES | AJINOMOTO KK (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6127361-A | FOR TREATMENT OR PREVENTION OF GASTROINTESTINAL MOVING FUNCTION DISORDERS, IRRITABLE BOWEL SYNDROME | AJINOMO CO., INC. (JP) | 2000-10-03 | — | — | US | disclosed |
| EP-0889043-A1 | 5,11-DIHYDRODIBENZ b,e] 1,4]OXAZEPINE DERIVATIVES AND DRUG COMPOSITIONS CONTAING THE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 1999-01-07 | — | — | EP | disclosed |