Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359002 | 0.96 | HRH3 (0.69) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| SCHEMBL7359013 | 0.96 | HRH3 (0.69) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL9752578 | 0.95 | HRH3 (0.67) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| SCHEMBL6802109 | 0.85 | HRH3 (0.68) | HRH3SIGMAR1SLC6A4 | |
| SCHEMBL10669091 | 0.84 | HRH3 (1.00) | HRH3SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL17294993 | 0.83 | HRH3 (0.97) | HRH3SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL8938430 | 0.81 | HRH3 (0.69) | HRH3SIGMAR1MEN1KMT2AHTR1A | |
| SCHEMBL4806889 | 0.81 | HRH3 (0.66) | HRH3SIGMAR1MEN1KMT2A | |
| SCHEMBL7355512 | 0.81 | HRH3 (0.66) | HRH3SIGMAR1MEN1KMT2A | |
| SCHEMBL4806896 | 0.81 | HRH3 (0.66) | HRH3SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1475373-A1 | 5,11-Dihydrodibenzo[b,e][1,4]-oxazepine derivatives as calcium channel antagonists | Ajinomoto Co., Inc. (JP) | 2004-11-10 | — | — | EP | disclosed |
| EP-1471060-A1 | 5,11-Dihydrodibenzo[b,e][1,4]-oxazepine derivatives as calcium channel antagonists | Ajinomoto Co., Inc. (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6528504-B2 | Compounds such as (R)-5,11-dihydro-5-(1-(4-methoxyphenethyl)-piperidine-2-ylmethyl) -dibenzo(b,e)(1,4) oxazepine are useful for treating or preventing abnormal motor functions of gastrointestinal tracts, e.g., irritable bowel syndrome. | AJINOMOTO CO., INC. (JP) | 2003-03-04 | — | — | US | disclosed |
| US-20020099047-A1 | Oxazepine derivatives and medicine containing the same | AJINOMOTO CO., INC. (JP) | 2002-07-25 | — | — | US | disclosed |
| EP-1142884-A1 | OXAZEPINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Ajinomoto Co., Inc. (JP) | 2001-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099047-A1 | Oxazepine derivatives and medicine containing the same | CACNG5, GRIK5, KCNB1 | HRH3 250/4885SIGMAR1 566/4885MEN1 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.