Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366493 | 0.81 | ABCB1 (0.40) | GHSRMMENAMPTMAPK1EPHX2 | |
| SCHEMBL7359978 | 0.79 | MME (0.41) | MMENOTUMACE | |
| SCHEMBL29193914 | 0.78 | POLB (0.36) | GHSRMMENAMPTMAPK1EPHX2 | |
| SCHEMBL7364717 | 0.76 | CYP4F2 (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL7365156 | 0.74 | NAMPT (0.34) | GHSRMMENAMPTMAPK1EPHX2 | |
| SCHEMBL7302752 | 0.73 | ACE (0.38) | MMEACE | |
| SCHEMBL7292698 | 0.71 | MME (0.38) | MME | |
| SCHEMBL7300905 | 0.71 | MME (0.64) | MME | |
| SCHEMBL30267728 | 0.70 | MME (0.37) | GHSRMMENAMPTEPHX2POLB | |
| SCHEMBL3700526 | 0.70 | MME (0.37) | GHSRMMENAMPTEPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407960-A | For cardiovascualr disorders, pain | SCHERING CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| WO-1991009840-A1 | MERCAPTOCYCLOACYL AMINOACID ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |