Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 5/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29193914 | 0.84 | POLB (0.36) | MMEGHSRP4HBMAPK1EPHX2 | |
| SCHEMBL7359095 | 0.81 | GHSR (0.34) | ABCB1MMEGHSRP4HBMAPK1 | |
| SCHEMBL7365156 | 0.80 | NAMPT (0.34) | ABCB1MMEGHSRP4HBMAPK1 | |
| SCHEMBL30267728 | 0.76 | MME (0.37) | MMEGHSREPHX2NAMPTPOLB | |
| SCHEMBL3700526 | 0.76 | MME (0.37) | MMEGHSREPHX2NAMPTPOLB | |
| SCHEMBL27006578 | 0.75 | POLB (0.38) | GHSRMAPK1EPHX2NAMPTPOLB | |
| SCHEMBL260410 | 0.75 | MME (0.38) | ABCB1MMEGHSRMAPK1EPHX2 | |
| SCHEMBL29456934 | 0.75 | MME (0.38) | ABCB1MMEGHSRMAPK1EPHX2 | |
| SCHEMBL10004678 | 0.75 | CYP4F2 (0.48) | P4HBCYP4F2CYP4A11 | |
| SCHEMBL32683822 | 0.74 | EPHX2 (0.39) | GHSRMAPK1EPHX2NAMPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407960-A | For cardiovascualr disorders, pain | SCHERING CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| WO-1991009840-A1 | MERCAPTOCYCLOACYL AMINOACID ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |