SCHEMBL7359104

SCHEMBL7359104

CCOC(=O)OC1(CCCCCc2ccc(Cl)cc2)CO1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
LMNA P02545 2/20 0.48
ABCB11 O95342 1/20 0.48
MAPK1 P28482 1/20 0.48
PPARA Q07869 1/20 0.39
NAAA Q02083 1/20 0.38
ALDH1A1 P00352 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11208706 1.00 MAPT (0.48) MAPTLMNAABCB11MAPK1PPARA
SCHEMBL11202315 0.95 MAPT (0.45) MAPTLMNAABCB11MAPK1PPARA
SCHEMBL11018171 0.93 MAPT (0.47) MAPTLMNAABCB11MAPK1PPARA
SCHEMBL11022819 0.91 MAPT (0.45) MAPTLMNAABCB11MAPK1PPARA
SCHEMBL11201942 0.88 THRA (0.36) MAPTLMNAABCB11MAPK1NAAA
SCHEMBL11206652 0.88 THRA (0.36) MAPTLMNAABCB11MAPK1NAAA
SCHEMBL11201202 0.88 KCNA3 (0.41) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL11203299 0.88 KCNA3 (0.41) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL11206024 0.88 KCNA3 (0.41) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL11208527 0.88 KCNA3 (0.41) MAPTLMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231367-B1 USE OF OXIRANCARBOXYLIC ACIDS FOR THE TREATMENT OF HYPERLIPEMIA Wolf, Horst P.O., Dr. (DE) 1991-07-24 EP disclosed
EP-0231367-A1 USE OF OXIRANCARBOXYLIC ACIDS FOR THE TREATMENT OF HYPERLIPEMIA. BYK GULDEN LOMBERG CHEM FAB (DE) 1987-08-12 EP disclosed
WO-1987000751-A2 USE OF OXIRANCARBOXYLIC ACIDS FOR THE TREATMENT OF HYPERLIPEMIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1987-02-12 WO disclosed
EP-0025192-B1 SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1983-05-11 EP disclosed
EP-0025192-A2 Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1981-03-18 EP disclosed