Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 8/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7357141 | 0.86 | F2 (0.38) | F10F2PRSS1 | |
| SCHEMBL7359107 | 0.85 | F2 (0.39) | F10F2PLA2G4APRSS1 | |
| Hydrochloric Acid SCHEMBL7360989 | 0.84 | F2 (0.38) | F10F2PLA2G4APRSS1 | |
| Hydrochloric Acid SCHEMBL7355413 | 0.84 | F2 (0.38) | F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7355969 | 0.83 | F2 (0.38) | F10F2PLA2G4APRSS1 | |
| Hydrochloric Acid SCHEMBL7362105 | 0.83 | PLA2G4A (0.38) | F10F2PLA2G4APRSS1 | |
| Hydrochloric Acid SCHEMBL7360554 | 0.83 | F2 (0.37) | F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7353252 | 0.82 | PLA2G4A (0.39) | F10F2PLA2G4APRSS1 | |
| Hydrochloric Acid SCHEMBL7352968 | 0.82 | F10 (0.36) | F10F2PLA2G4APRSS1KMT2A | |
| Iodide SCHEMBL7354314 | 0.82 | F2 (0.40) | F10F2PRSS1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |