SCHEMBL7359196

SCHEMBL7359196

C#COC(=O)OC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
DGAT1 O75907 1/20 0.34
HDAC6 Q9UBN7 2/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11877904 0.77 ELANE (0.36) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL5789929 0.75 ELANE (0.39) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL372342 0.74
SCHEMBL29121 0.74 DGAT1 (0.46) ELANEDGAT1HDAC6HDAC1HDAC2
Methyl Alcohol SCHEMBL28820308 0.72 DGAT1 (0.43) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL27351077 0.72 DGAT1 (0.43) ELANEDGAT1HDAC6HDAC1HDAC2
Ammonia Solution, Strong SCHEMBL9998492 0.72 DGAT1 (0.43) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL28114416 0.72 DGAT1 (0.43) ELANEDGAT1HDAC6HDAC1HDAC2
Fluoride SCHEMBL2692246 0.72 DGAT1 (0.43) ELANEDGAT1HDAC6HDAC1HDAC2
Hydrogen Peroxide SCHEMBL28079587 0.72 DGAT1 (0.43) ELANEDGAT1HDAC6HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3313851-B1 NEW HYDROXYESTER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SERVIER LAB (FR) 2019-11-06 EP claimed
EP-2692728-B1 NOVEL FURANONE DERIVATIVE CARNA BIOSCIENCES INC (JP) 2018-07-04 EP claimed
EP-2646427-B1 QUINOLIN-4(1H)-ONE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASES KITHER BIOTECH S R L (IT) 2016-02-03 EP claimed
EP-2189443-B1 TRICYCLIC AMIDE COMPOUND RES FOUND ITSUU LAB (JP) 2013-10-23 EP claimed
EP-0370454-B1 Renin-inhibiting amino diol derivatives HOECHST AG (DE) 1994-04-20 EP claimed
US-9545636-B2 Method for processing mineral material containing acid-consuming carbonate and precious metal in sulfide minerals NEWMONT USA LIMITED (US) 2017-01-17 US disclosed
US-20160074872-A1 METHOD FOR PROCESSING MINERAL MATERIAL CONTAINING ACID-CONSUMING CARBONATE AND PRECIOUS METAL IN SULFIDE MINERALS NEWMONT USA LIMITED 2016-03-17 US disclosed