Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.57 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.57 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.57 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.57 |
| ▸ | DAO | P14920 | 4/20 | 0.53 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | PARG | Q86W56 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545573 | 0.86 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4DAO | |
| SCHEMBL3263393 | 0.81 | DAO (0.66) | DAOADORA2AADORA2BPDE2APDE3B | |
| SCHEMBL9365003 | 0.81 | DAO (0.70) | GRIA1GRIA2GRIA3GRIA4DAO | |
| SCHEMBL31439104 | 0.81 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARG | |
| SCHEMBL5550237 | 0.81 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4DAO | |
| SCHEMBL9398023 | 0.81 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4DAO | |
| SCHEMBL8403660 | 0.81 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4PARG | |
| SCHEMBL7968233 | 0.81 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4PARG | |
| Hydrochloric Acid SCHEMBL9395721 | 0.79 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4PARG | |
| SCHEMBL9395591 | 0.78 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057304-A | Quinoxaline-phosphonic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |