Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PARG | Q86W56 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21848191 | 0.86 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4TP53 | |
| Hydrochloric Acid SCHEMBL27488313 | 0.85 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4TP53 | |
| SCHEMBL29502169 | 0.82 | MAPT (0.59) | TP53MAPTMETAP2LMNAAURKA | |
| SCHEMBL625508 | 0.82 | MAPT (0.59) | TP53MAPTMETAP2LMNAAURKA | |
| SCHEMBL7359339 | 0.81 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9398023 | 0.79 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL31439104 | 0.79 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL5550237 | 0.79 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4PARG | |
| SCHEMBL8403660 | 0.79 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| Hydrochloric Acid SCHEMBL9395721 | 0.78 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-0315959-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-03-02 | — | — | EP | disclosed |
| US-5026704-A | Neuroleptic agent, quisqualate-antagonist | NOVO NORDISK A/S (DK) | 1991-06-25 | — | — | US | disclosed |
| US-4948794-A | NEUROLEPTIC AGENTS | A/S FERROSAN (DK) | 1990-08-14 | — | — | US | disclosed |