⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051529 | 0.97 | — | — | |
| SCHEMBL608066 | 0.91 | — | — | |
| SCHEMBL610809 | 0.84 | — | — | |
| SCHEMBL9405330 | 0.78 | ADH1B (0.34) | — | |
| SCHEMBL6873949 | 0.75 | ADH1B (0.40) | — | |
| SCHEMBL2021416 | 0.75 | ADH1B (0.40) | — | |
| SCHEMBL3848698 | 0.75 | ADH1B (0.40) | — | |
| SCHEMBL5462678 | 0.73 | ADH1B (0.39) | — | |
| SCHEMBL29860701 | 0.71 | ADH1B (0.36) | — | |
| SCHEMBL6766085 | 0.71 | ADH1B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10081601-B2 | Glucocerebrosidase modulators and uses thereof | ALECTOS THERAPEUTICS INC. (CA) | 2018-09-25 | — | — | US | disclosed |
| US-20180009761-A1 | GLUCOCEREBROSIDASE MODULATORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2018-01-11 | — | — | US | disclosed |
| US-9796680-B2 | Glucocerebrosidase modulators and uses thereof | ALECTOS THERAPEUTICS INC. (CA) | 2017-10-24 | — | — | US | disclosed |
| US-20170029379-A1 | GLUCOCEREBROSIDASE MODULATORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2017-02-02 | — | — | US | disclosed |
| EP-3087056-A1 | GLUCOCEREBROSIDASE MODULATORS AND USES THEREOF | Alectos Therapeutics Inc. (CA) | 2016-11-02 | — | — | EP | disclosed |
| WO-2015095963-A1 | GLUCOCEREBROSIDASE MODULATORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2015-07-02 | — | — | WO | disclosed |
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |