Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 11/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358077 | 0.91 | CACNA1B (0.64) | CACNA1BMAOBMAOAKDM4ENPC1 | |
| SCHEMBL7037028 | 0.83 | CACNA1B (0.74) | CACNA1BMAOBMAOAKMT2A | |
| SCHEMBL7037026 | 0.80 | CACNA1B (0.62) | CACNA1BMAOBMAOAKDM4ENPC1 | |
| SCHEMBL7421288 | 0.77 | CACNA1B (0.49) | CACNA1BMAOB | |
| SCHEMBL7352079 | 0.74 | CACNA1B (0.62) | CACNA1BMEN1KMT2AJAK2JAK1 | |
| SCHEMBL7356401 | 0.74 | CACNA1B (0.62) | CACNA1BNPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL7349970 | 0.72 | CACNA1B (0.63) | CACNA1BMEN1KMT2A | |
| SCHEMBL7352934 | 0.72 | CACNA1B (0.61) | CACNA1BMEN1KMT2AJAK2JAK1 | |
| SCHEMBL7357575 | 0.70 | CACNA1B (0.47) | CACNA1BMEN1KMT2A | |
| SCHEMBL7349295 | 0.70 | CACNA1B (0.56) | CACNA1BMEN1KMT2AJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |