Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.48 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395635 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BITGA2HRH3S1PR1 | |
| Hydrochloric Acid SCHEMBL7385436 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BITGA2HRH3FFAR1 | |
| SCHEMBL7394485 | 0.80 | S1PR1 (0.54) | ITGB3ITGA2BITGA2S1PR1FFAR1 | |
| Hydrochloric Acid SCHEMBL7395305 | 0.79 | S1PR1 (0.53) | ITGB3ITGA2BITGA2S1PR1FFAR1 | |
| Hydrochloric Acid SCHEMBL7383647 | 0.78 | ITGB3 (0.49) | ITGB3ITGA2BITGA2 | |
| Hydrochloric Acid SCHEMBL7485800 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BITGA2HRH3S1PR1 | |
| Hydrochloric Acid SCHEMBL8417336 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BITGA2HRH3FFAR1 | |
| Hydrochloric Acid SCHEMBL7392502 | 0.76 | S1PR1 (0.50) | ITGB3ITGA2BITGA2HRH3S1PR1 | |
| Hydrochloric Acid SCHEMBL7395166 | 0.76 | ITGB3 (0.48) | ITGB3ITGA2BITGA2HRH3S1PR1 | |
| Hydrochloric Acid SCHEMBL7398273 | 0.75 | ITGB3 (0.50) | ITGB3ITGA2BITGA2S1PR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | claimed |
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | disclosed |