Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357687 | 0.89 | ANPEP (0.34) | ANPEPERAP2ERAP1TSHRCYP3A4 | |
| SCHEMBL1619040 | 0.81 | ANPEP (0.41) | ANPEPERAP2ERAP1TSHRCYP3A4 | |
| SCHEMBL1752333 | 0.81 | ANPEP (0.41) | ANPEPERAP2ERAP1TSHRCYP3A4 | |
| SCHEMBL171329 | 0.79 | MEN1 (0.43) | ANPEPERAP2ERAP1TSHRCYP3A4 | |
| SCHEMBL2099439 | 0.78 | PIK3CD (0.45) | CYP3A4CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL1619039 | 0.78 | ANPEP (0.38) | ANPEPERAP2ERAP1TSHRCYP3A4 | |
| SCHEMBL8558131 | 0.76 | USP2 (0.47) | ANPEPERAP2ERAP1TSHRCYP3A4 | |
| SCHEMBL8558133 | 0.76 | USP2 (0.47) | ANPEPERAP2ERAP1TSHRCYP3A4 | |
| SCHEMBL14697239 | 0.68 | KDM2B (0.33) | — | |
| SCHEMBL6897914 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |