Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369394 | 0.85 | SMYD3 (0.50) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7362731 | 0.83 | SMYD3 (0.50) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7362190 | 0.81 | ALDH1A1 (0.43) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7360180 | 0.80 | ALDH1A1 (0.44) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7367819 | 0.79 | ALDH1A1 (0.43) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7368017 | 0.79 | ACE (0.47) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7361961 | 0.78 | ACE (0.46) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8718282 | 0.78 | ALDH1A1 (0.42) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7361906 | 0.76 | CYP1A2 (0.46) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8720975 | 0.76 | ACE (0.45) | ACELMNAKCNK3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432159-A | N-(α-substituted-pyridinyl)carbonyl dipeptide antihypertensive agents | LACER S.A. (ES) | 1995-07-11 | — | — | US | disclosed |
| WO-1992015608-A1 | N-(α-SUBSTITUTED-PYRIDINYL)CARBONYL DIPEPTIDE ANTIHYPERTENSIVE AGENTS | LACER S.A. (ES) | 1992-09-17 | — | — | WO | disclosed |