Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 9/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360123 | 0.87 | AIMP2 (0.46) | AIMP2TSHRMEN1KMT2ACTSS | |
| SCHEMBL7363128 | 0.85 | TSHR (0.48) | TSHRCYP3A4CCR1SMN1; SMN2KDM4E | |
| SCHEMBL7357371 | 0.85 | CYP3A4 (0.49) | AIMP2TSHRMEN1KMT2ACTSS | |
| SCHEMBL19839941 | 0.80 | AIMP2 (0.55) | AIMP2TSHRMEN1KMT2ACTSS | |
| SCHEMBL30597934 | 0.80 | AIMP2 (0.55) | AIMP2TSHRMEN1KMT2ACTSS | |
| SCHEMBL7363131 | 0.74 | TSHR (0.47) | TSHRCYP3A4CCR1SMN1; SMN2KDM4E | |
| SCHEMBL7397775 | 0.74 | GAA (0.48) | TSHRMEN1KMT2ACAPN1CYP3A4 | |
| SCHEMBL22500236 | 0.72 | CCR1 (0.62) | AIMP2TSHRMEN1KMT2ACTSS | |
| SCHEMBL19853291 | 0.71 | CTSK (0.60) | AIMP2TSHRMEN1KMT2ACTSS | |
| SCHEMBL22591021 | 0.71 | CTSK (0.60) | AIMP2TSHRMEN1KMT2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |