Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354812 | 0.91 | KDM4E (0.42) | SIGMAR1MAPTKDM4EHTR1APARP1 | |
| Hydrochloric Acid SCHEMBL7354409 | 0.90 | KDM4E (0.42) | SIGMAR1MAPTKDM4EHTR1APARP1 | |
| SCHEMBL7354626 | 0.88 | KDM4E (0.43) | SIGMAR1MAPTKDM4EHTR1APARP1 | |
| Hydrochloric Acid SCHEMBL7355986 | 0.87 | SIGMAR1 (0.44) | SIGMAR1MAPTKDM4EHTR1ADRD3 | |
| SCHEMBL7361126 | 0.87 | KMT2A (0.42) | SIGMAR1MAPTKDM4EHTR1APARP1 | |
| SCHEMBL7355443 | 0.87 | KDM4E (0.42) | SIGMAR1MAPTKDM4EHTR1APARP1 | |
| SCHEMBL7360192 | 0.87 | KDM4E (0.42) | SIGMAR1MAPTKDM4EHTR1APARP1 | |
| SCHEMBL7361901 | 0.87 | KDM4E (0.41) | SIGMAR1MAPTKDM4EHTR1APARP1 | |
| SCHEMBL7355373 | 0.86 | KDM4E (0.42) | SIGMAR1MAPTKDM4EHTR1APARP1 | |
| SCHEMBL7353274 | 0.86 | KDM4E (0.42) | SIGMAR1MAPTKDM4EHTR1APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |