Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 7/20 | 0.35 |
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7353265 | 0.81 | F2 (0.40) | F2F10ALDH1A1PRSS1 | |
| Iodide SCHEMBL7355329 | 0.78 | F2 (0.51) | F2F10ALDH1A1PRSS1GAA | |
| Hydrochloric Acid SCHEMBL7358829 | 0.78 | F2 (0.39) | F2F10ALDH1A1PRSS1KMT2A | |
| Hydrochloric Acid SCHEMBL7351180 | 0.77 | PTGER1 (0.40) | F2ALDH1A1PRSS1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7360238 | 0.77 | F2 (0.49) | F2F10ALDH1A1PRSS1GAA | |
| Hydrochloric Acid SCHEMBL7355792 | 0.77 | F2 (0.41) | F2F10ALDH1A1PRSS1KMT2A | |
| Hydrochloric Acid SCHEMBL7354708 | 0.76 | F2 (0.48) | KEAP1NFE2L2F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL7360552 | 0.76 | F2 (0.52) | F2F10ALDH1A1PRSS1GAA | |
| Hydrochloric Acid SCHEMBL7358442 | 0.76 | ALDH1A1 (0.45) | F2F10ALDH1A1PRSS1GAA | |
| Hydrochloric Acid SCHEMBL7360087 | 0.76 | F2 (0.39) | F2F10ALDH1A1PRSS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |