Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.63 |
| ▸ | TMPRSS11D | O60235 | 12/20 | 0.62 |
| ▸ | F10 | P00742 | 3/20 | 0.60 |
| ▸ | PLG | P00747 | 3/20 | 0.60 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353953 | 0.90 | TMPRSS11D (0.65) | F2TMPRSS11DF10PLG | |
| SCHEMBL7106028 | 0.89 | TMPRSS11D (0.68) | F2TMPRSS11DF10PLG | |
| Hydrochloric Acid SCHEMBL7140902 | 0.88 | TMPRSS11D (0.67) | F2TMPRSS11DF10PLG | |
| SCHEMBL7365085 | 0.85 | TMPRSS11D (0.64) | F2TMPRSS11DF10PLG | |
| SCHEMBL7107381 | 0.84 | F2 (0.66) | F2TMPRSS11DF10PLG | |
| SCHEMBL8770719 | 0.84 | TMPRSS11D (0.62) | F2TMPRSS11DF10PLG | |
| Hydrochloric Acid SCHEMBL9228058 | 0.83 | F2 (0.65) | F2TMPRSS11DF10PLG | |
| SCHEMBL23752316 | 0.83 | F2 (0.74) | F2TMPRSS11DF10PLG | |
| SCHEMBL15077024 | 0.83 | F2 (0.74) | F2TMPRSS11DF10PLG | |
| SCHEMBL7148728 | 0.83 | F2 (0.74) | F2TMPRSS11DF10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796271-B1 | DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AG (DE) | 2000-02-02 | — | — | EP | disclosed |
| EP-0796271-A1 | NEW DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017860-A1 | NEW DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |