Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.52 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31089857 | 0.90 | HTR2A (0.60) | HTR2AMEN1KMT2AGAAKDM4E | |
| SCHEMBL6615000 | 0.88 | HTR2A (0.68) | HTR2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL11068196 | 0.85 | HTR2A (0.67) | HTR2AMEN1KMT2AMAPTTDP1 | |
| SCHEMBL31295159 | 0.83 | HTR2A (0.71) | HTR2AKMT2AKDM4EPOLBMAPT | |
| SCHEMBL23805297 | 0.82 | HTR2A (0.67) | HTR2AKMT2AKDM4EMAPTTDP1 | |
| SCHEMBL11263785 | 0.82 | HTR2A (0.67) | HTR2AKMT2AKDM4EMAPTTDP1 | |
| SCHEMBL6617210 | 0.82 | HTR2A (0.66) | HTR2AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7390324 | 0.81 | HTR2A (0.55) | HTR2AALDH1A1MCL1PTGER1SRD5A2 | |
| SCHEMBL6770793 | 0.81 | KDM4E (0.64) | HTR2AMEN1KMT2AGAAKDM4E | |
| SCHEMBL23805211 | 0.80 | HTR2A (0.71) | HTR2AKDM4EMAPTLTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014709-A2 | CALCIUM CHANNEL ANTAGONISTS AND METHODOLOGY FOR THEIR IDENTIFICATION | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1992-09-03 | — | — | WO | disclosed |