Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416522 | 0.80 | CA1 (0.40) | TAAR1ALDH1A1MAPT | |
| SCHEMBL6298397 | 0.78 | NAAA (0.32) | TAAR1DRD2DRD3NAAA | |
| SCHEMBL6302847 | 0.78 | NAAA (0.32) | TAAR1DRD2DRD3NAAA | |
| SCHEMBL6690811 | 0.78 | NAAA (0.32) | TAAR1DRD2DRD3NAAA | |
| SCHEMBL5165572 | 0.61 | TAAR1 (0.37) | TAAR1DRD2DRD3NAAAHPGD | |
| SCHEMBL1538017 | 0.60 | — | — | |
| SCHEMBL12594976 | 0.59 | TAAR1 (0.54) | TAAR1DRD2DRD3SLC1A3SLC1A2 | |
| SCHEMBL6608641 | 0.58 | ASAH1 (0.37) | MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2009601 | 0.57 | — | — | |
| SCHEMBL5303749 | 0.57 | TAAR1 (0.55) | TAAR1DRD2DRD3SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |