Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770440 | 0.82 | ARG1 (0.38) | — | |
| SCHEMBL6290400 | 0.82 | ARG1 (0.38) | — | |
| SCHEMBL1770442 | 0.82 | ARG1 (0.38) | — | |
| SCHEMBL4718947 | 0.80 | HTT (0.31) | — | |
| SCHEMBL5694169 | 0.80 | HTT (0.31) | — | |
| Hydrochloric Acid SCHEMBL15776085 | 0.78 | HTT (0.30) | — | |
| Hydrochloric Acid SCHEMBL15776082 | 0.78 | HTT (0.30) | — | |
| SCHEMBL15046738 | 0.78 | KMT2A (0.38) | — | |
| SCHEMBL6432101 | 0.78 | KMT2A (0.38) | — | |
| SCHEMBL6432107 | 0.78 | KMT2A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077978-A1 | NOVEL SUBSTITUTED ARYL HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058531-A1 | NOVEL SUBSTITUTED ARYL HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-11-18 | — | — | WO | claimed |
| WO-2002083112-A2 | METHOD FOR THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE | WYETH HOLDINGS CORPORATION (US) | 2002-10-24 | — | — | WO | disclosed |
| EP-1077978-A1 | NOVEL SUBSTITUTED ARYL HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058531-A1 | NOVEL SUBSTITUTED ARYL HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-11-18 | — | — | WO | disclosed |