Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.72 |
| ▸ | ITGAV | P06756 | 19/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672674 | 0.86 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL6951803 | 0.84 | ITGB3 (0.73) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL6947538 | 0.84 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL6941347 | 0.84 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7333365 | 0.84 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7340046 | 0.83 | ITGB3 (0.89) | ITGB3ITGAVITGA2B | |
| SCHEMBL7361297 | 0.81 | ITGB3 (0.54) | ITGB3ITGAVITGA2B | |
| SCHEMBL7442340 | 0.79 | ITGB3 (0.59) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL8467478 | 0.79 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL7363355 | 0.78 | ITGB3 (0.76) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |