SCHEMBL7360797

SCHEMBL7360797

NC(CCC[C@H](N)C(=O)O)C(=O)OCc1ccccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 4/20 0.55
L3MBTL1 Q9Y468 1/20 0.46
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
NR4A2 P43354 1/20 0.43
IDO1 P14902 2/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
KIF11 P52732 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9333977 1.00 SLC1A5 (0.55) SLC1A5L3MBTL1PPARGPPARANR4A2
SCHEMBL7365885 0.90 SLC1A5 (0.46) SLC1A5L3MBTL1PPARGPPARANR4A2
SCHEMBL10335615 0.85 SLC1A5 (0.54) SLC1A5PPARGPPARANR4A2IDO1
SCHEMBL6743997 0.84 SLC1A5 (0.43) SLC1A5L3MBTL1NR4A2IDO1CASP3
SCHEMBL10458548 0.83 MAPT (0.45) SLC1A5PPARGPPARAIDO1MMP1
SCHEMBL30600462 0.83 KEAP1 (0.57) SLC1A5L3MBTL1CASP3SENP8SENP7
SCHEMBL29400837 0.83 KEAP1 (0.57) SLC1A5L3MBTL1CASP3SENP8SENP7
SCHEMBL30600458 0.82 KEAP1 (0.58) SLC1A5L3MBTL1MMP2MMP9CYP1A2
SCHEMBL4413196 0.82 KEAP1 (0.58) SLC1A5L3MBTL1MMP2MMP9CYP1A2
SCHEMBL3925964 0.82 KEAP1 (0.58) SLC1A5L3MBTL1MMP2MMP9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4960881-A REACTING AMINO ACID WITH ALPHA-CHLORINATED CARBONATE IN SOLVENT IN PRESENCE OF ACID SCAVENGER SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1990-10-02 US claimed
EP-0578728-B1 PLATELET AGGREGATION INHIBITORS HAVING HIGH SPECIFICITY FOR GP IIbIIIa GENENTECH INC (US) 1998-07-01 EP disclosed
US-5493007-A OLIGOPEPTIDE GENENTECH, INC. (US) 1996-02-20 US disclosed
EP-0315367-B1 Polypeptides ICI PLC (GB) 1994-04-06 EP disclosed
EP-0578728-A1 PLATELET AGGREGATION INHIBITORS HAVING HIGH SPECIFICITY FOR GP IIbIIIa GENENTECH, INC. (US) 1994-01-19 EP disclosed
WO-1992017492-A1 PLATELET AGGREGATION INHIBITORS HAVING HIGH SPECIFICITY FOR GP IIbIII¿a? GENENTECH, INC. (US) 1992-10-15 WO disclosed
US-4960881-A REACTING AMINO ACID WITH ALPHA-CHLORINATED CARBONATE IN SOLVENT IN PRESENCE OF ACID SCAVENGER SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1990-10-02 US disclosed
US-4623716-A CYCLIZATION OF CYSTEINE COMPONENTS USV PHARMACEUTICAL CORP. (US) 1986-11-18 US disclosed