Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6107967 | 0.99 | F10 (0.50) | F10F2LMNATP53GAA | |
| Hydrochloric Acid SCHEMBL5225021 | 0.87 | F10 (0.55) | F10F2LMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5225771 | 0.85 | F10 (0.56) | F10F2TSHRELANEALDH1A1 | |
| Hydrochloric Acid SCHEMBL5221061 | 0.85 | ME3 (0.59) | F10F2ELANEKDM4ERXFP1 | |
| SCHEMBL6109086 | 0.85 | F10 (0.50) | F10F2TP53ELANEKDM4E | |
| SCHEMBL6106118 | 0.84 | BDKRB1 (0.48) | F10F2LMNAELANEKDM4E | |
| Hydrochloric Acid SCHEMBL5223873 | 0.83 | KDM4E (0.51) | F10F2TP53GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5223652 | 0.83 | F10 (0.55) | F10F2ELANEKDM4ERXFP1 | |
| Hydrochloric Acid SCHEMBL6108323 | 0.83 | BDKRB1 (0.47) | F10F2LMNAELANEKDM4E | |
| Hydrochloric Acid SCHEMBL5224177 | 0.83 | F10 (0.57) | F10F2ELANERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |