Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 17/20 | 0.57 |
| ▸ | ACHE | P22303 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7357894 | 0.81 | HTR4 (0.71) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| SCHEMBL7360030 | 0.80 | HTR4 (0.69) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| SCHEMBL17709637 | 0.74 | HTR4 (0.72) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| SCHEMBL7354794 | 0.73 | HTR4 (1.00) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| SCHEMBL7350297 | 0.72 | HTR4 (1.00) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| SCHEMBL548885 | 0.72 | HTR4 (0.69) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7356067 | 0.72 | HTR4 (0.98) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7358764 | 0.72 | HTR4 (0.78) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL1078403 | 0.72 | HTR4 (0.68) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7356881 | 0.72 | HTR4 (0.98) | HTR4ACHEMEN1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-B1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX INC (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5763458-A | NERVOUS SYSTEM DISORDERS, ANXIETY, ANTIDEPRESSANTS AND COGNITION ACTIVATORS | SYNTEX (U.S.A.) INC. (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1994027965-A1 | NOVEL 1-PHENYLALKANONE 5-HT4 RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1994-12-08 | — | — | WO | disclosed |