Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363380 | 0.86 | ITGB3 (0.40) | CHRM5HTR2AFFAR4CHRM1FFAR1 | |
| SCHEMBL7356283 | 0.75 | ITGB3 (0.43) | CHRM5KDM4EALOX15TSHRSIRT1 | |
| SCHEMBL7362405 | 0.73 | CHRM5 (0.43) | CHRM5HTR2ACHRM1CASP3CASP7 | |
| SCHEMBL7362408 | 0.73 | CHRM5 (0.38) | CHRM5HTR2ACHRM1CASP3CASP7 | |
| SCHEMBL7362910 | 0.73 | CHRM5 (0.37) | CHRM5HTR2ACHRM1CASP3CASP7 | |
| SCHEMBL7362403 | 0.72 | CHRM5 (0.38) | CHRM5HTR2ACHRM1CASP3CASP7 | |
| SCHEMBL7359698 | 0.72 | ITGB3 (0.57) | FFAR4KDM4EALOX15TSHRSIRT1 | |
| SCHEMBL7359718 | 0.70 | ITGB3 (0.41) | CHRM5FFAR4KDM4EALOX15TSHR | |
| SCHEMBL7354009 | 0.69 | ITGB3 (0.44) | FFAR4KDM4EALOX15TSHRSIRT1 | |
| SCHEMBL7353334 | 0.69 | ITGB3 (0.45) | FFAR4KDM4EALOX15TSHRSIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993008174-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR | GENENTECH, INC. (US) | 1993-04-29 | — | — | WO | disclosed |