Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.60 |
| ▸ | ECE1 | P42892 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.54 |
| ▸ | ITGAL | P20701 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365431 | 1.00 | ACE (0.60) | ACEECE1ALOX15ITGB2ICAM1 | |
| SCHEMBL3848913 | 0.82 | ACE (0.67) | ACEECE1ALOX15ITGB2ICAM1 | |
| SCHEMBL3851280 | 0.82 | ACE (0.67) | ACEECE1ALOX15ITGB2ICAM1 | |
| SCHEMBL7359906 | 0.82 | ECE1 (0.60) | ACEECE1MMP2MMP9 | |
| SCHEMBL5123003 | 0.82 | ALOX15 (0.67) | ACEECE1ALOX15ITGB2ICAM1 | |
| SCHEMBL5123004 | 0.82 | ALOX15 (0.67) | ACEECE1ALOX15ITGB2ICAM1 | |
| SCHEMBL11589471 | 0.81 | ACE (0.65) | ACEECE1ALOX15ITGB2ICAM1 | |
| SCHEMBL28973296 | 0.81 | ACE (0.65) | ACEECE1ALOX15ITGB2ICAM1 | |
| SCHEMBL17859830 | 0.81 | ALOX15 (0.60) | ACEECE1ALOX15ITGB2ICAM1 | |
| SCHEMBL7367496 | 0.81 | ALOX15 (0.50) | ACEECE1ALOX15ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888341-A1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032874-A1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1997-09-12 | — | — | WO | disclosed |