Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | PDE6A | P16499 | 1/20 | 0.41 |
| ▸ | PDE6G | P18545 | 1/20 | 0.41 |
| ▸ | PDE6B | P35913 | 1/20 | 0.41 |
| ▸ | PDE6C | P51160 | 1/20 | 0.41 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391271 | 0.85 | PPARA (0.41) | PPARAPPARGPPARDCCR2GAA | |
| SCHEMBL7392974 | 0.85 | PPARA (0.41) | PPARAPPARGPPARDCCR2GAA | |
| SCHEMBL7391274 | 0.85 | PPARA (0.41) | PPARAPPARGPPARDCCR2GAA | |
| SCHEMBL7364879 | 0.81 | PPARA (0.47) | PPARAPPARGPPARDGAAPDE5A | |
| SCHEMBL7364158 | 0.80 | PPARA (0.47) | PPARAPPARGPPARDCCR2GAA | |
| SCHEMBL7563607 | 0.80 | PPARA (0.47) | PPARAPPARGPPARDCCR2GAA | |
| SCHEMBL7364151 | 0.80 | PPARA (0.47) | PPARAPPARGPPARDCCR2GAA | |
| SCHEMBL7367480 | 0.79 | PPARA (0.47) | PPARAPPARGPPARDGAAPDE5A | |
| SCHEMBL7362850 | 0.78 | PPARA (0.44) | PPARAPPARGPPARDGAAPDE5A | |
| SCHEMBL6943273 | 0.75 | PPARA (0.55) | PPARAPPARGPPARDGAAPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |