Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | PDE4A | P27815 | 3/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396306 | 0.91 | MEN1 (0.58) | MEN1EPHX1KMT2AALDH1A1PDE4A | |
| SCHEMBL6816260 | 0.91 | KMT2A (0.58) | MEN1EPHX1KMT2AALDH1A1PDE4A | |
| SCHEMBL7367212 | 0.90 | MEN1 (0.57) | MEN1EPHX1KMT2AALDH1A1PDE4A | |
| SCHEMBL9275728 | 0.90 | MEN1 (0.57) | MEN1EPHX1KMT2AALDH1A1PDE4A | |
| SCHEMBL9273289 | 0.89 | MEN1 (0.56) | MEN1EPHX1KMT2AALDH1A1PDE4A | |
| SCHEMBL8571660 | 0.88 | KMT2A (0.61) | MEN1EPHX1KMT2APDE4APDE4B | |
| SCHEMBL8570021 | 0.88 | MEN1 (0.61) | MEN1EPHX1KMT2APDE4APDE4B | |
| SCHEMBL9276408 | 0.88 | MEN1 (0.55) | MEN1EPHX1KMT2AALDH1A1PDE4A | |
| SCHEMBL7367210 | 0.88 | MEN1 (0.55) | MEN1EPHX1KMT2AALDH1A1PDE4A | |
| SCHEMBL9266624 | 0.88 | ALDH1A1 (0.55) | MEN1EPHX1KMT2AALDH1A1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538384-A4 | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5393788-A | Phenylalkyl oxamides | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |