Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553235 | 0.80 | TRPA1 (0.33) | — | |
| SCHEMBL9720383 | 0.78 | SLC22A6 (0.39) | BHMTSLC22A6CACNA2D1TDP1CACNB3 | |
| SCHEMBL27632960 | 0.77 | TSHR (0.36) | MAPT | |
| SCHEMBL3234240 | 0.75 | TRPA1 (0.31) | — | |
| SCHEMBL15978108 | 0.75 | CACNA2D1 (0.55) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL10792704 | 0.74 | — | — | |
| SCHEMBL27599259 | 0.74 | — | — | |
| SCHEMBL258152 | 0.74 | SLC22A6 (0.50) | BHMTSLC22A6CACNA2D1TDP1CACNB3 | |
| SCHEMBL4903609 | 0.73 | — | — | |
| SCHEMBL5505839 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121623-A1 | IONIZATION RADIATION IMAGEABLE PHOTOPOLYMER COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-08-08 | — | — | EP | claimed |
| WO-2000020926-A9 | IONIZATION RADIATION IMAGEABLE PHOTOPOLYMER COMPOSITIONS | DU PONT (US) | 2000-09-14 | — | — | WO | claimed |
| WO-2000020926-A1 | IONIZATION RADIATION IMAGEABLE PHOTOPOLYMER COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-04-13 | — | — | WO | claimed |
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| US-4837204-A | RENIN INHIBITORS; HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1989-06-06 | — | — | US | disclosed |