Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484218 | 0.80 | PARP1 (0.60) | PARP1ERN1 | |
| SCHEMBL29952788 | 0.80 | PARP1 (0.60) | PARP1ERN1 | |
| SCHEMBL1512811 | 0.79 | PARP1 (0.39) | PARP1ERN1CYP2A6 | |
| SCHEMBL10544843 | 0.79 | ERN1 (0.42) | PARP1ERN1 | |
| SCHEMBL10602912 | 0.79 | ERN1 (0.44) | PARP1ERN1CYP2A6 | |
| SCHEMBL9846177 | 0.75 | PARP1 (0.36) | PARP1ERN1CYP2A6 | |
| SCHEMBL8551468 | 0.74 | KCNH2 (0.35) | PARP1 | |
| SCHEMBL8551471 | 0.74 | KCNH2 (0.35) | PARP1 | |
| SCHEMBL23363737 | 0.72 | NFE2L2 (0.39) | PARP1 | |
| SCHEMBL23363740 | 0.72 | NFE2L2 (0.39) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138357-B2 | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field | GIULIANI INTERNATIONAL LIMITED (IE) | 2012-03-20 | — | — | US | disclosed |
| US-20090118357-A1 | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field | GIULIANI INTERNATIONAL LIMITED (IE) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118357-A1 | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field | EGFR, ERBB3, FGFR3 | PARP1 4434/4885ERN1 2723/4885CYP2A6 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.