Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16822939 | 0.89 | HRH3 (0.46) | HRH3 | |
| SCHEMBL18552417 | 0.84 | HRH3 (0.42) | HRH3 | |
| SCHEMBL3274096 | 0.84 | HRH3 (0.55) | HRH3 | |
| SCHEMBL28297004 | 0.84 | SIGMAR1 (0.45) | — | |
| SCHEMBL2811370 | 0.81 | HRH3 (0.54) | HRH3 | |
| SCHEMBL11044966 | 0.81 | EPHX2 (0.54) | — | |
| SCHEMBL16532717 | 0.81 | SIGMAR1 (0.45) | — | |
| SCHEMBL28238752 | 0.80 | DRD4 (0.49) | HRH3 | |
| SCHEMBL6120780 | 0.80 | SMN1; SMN2 (0.43) | HRH3 | |
| SCHEMBL1830606 | 0.79 | POLB (0.49) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588702-A | N-substituted phenyl-4-one derivatives, and preparation method and application thereof | UNIV ZHEJIANG | 2014-02-19 | — | — | CN | disclosed |
| CN-101228127-B | Piperidine derivatives | BANYU PHARMA CO LTD | 2012-05-16 | — | — | CN | disclosed |
| US-8138206-B2 | Piperidine derivative | MSD. K.K. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20090137576-A1 | Novel Piperidine Derivative | MSD K.K. (JP) | 2009-05-28 | — | — | US | disclosed |
| CN-101228127-A | Novel Piperidine Derivatives | BANYU PHARMA CO LTD (JP) | 2008-07-23 | — | — | CN | disclosed |
| EP-1892241-A1 | NOVEL PIPERIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137576-A1 | Novel Piperidine Derivative | HRH4, HRH3, HRH1 | HRH3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.