Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 5/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7362863 | 0.99 | LTA4H (0.49) | LTA4HEPHX2BCHEHRH3HTT | |
| Hydrochloric Acid SCHEMBL7364142 | 0.94 | BCHE (0.48) | LTA4HEPHX2BCHEHRH3HTT | |
| SCHEMBL7440022 | 0.81 | LTA4H (0.48) | LTA4HEPHX2BCHEHRH3HTT | |
| Hydrochloric Acid SCHEMBL7371611 | 0.81 | TDP1 (0.38) | LTA4HEPHX2HRH3 | |
| Hydrochloric Acid SCHEMBL7447695 | 0.80 | LTA4H (0.47) | LTA4HEPHX2BCHEHRH3HTT | |
| Hydrochloric Acid SCHEMBL7369765 | 0.72 | LTA4H (0.51) | LTA4HHRH3HTTKMT2ALMNA | |
| SCHEMBL12040562 | 0.72 | LTA4H (0.77) | LTA4HEPHX2BCHEMGLLLMNA | |
| SCHEMBL12630258 | 0.72 | LTA4H (0.77) | LTA4HEPHX2BCHEMGLLLMNA | |
| SCHEMBL11473762 | 0.71 | LTA4H (0.66) | LTA4HEPHX2BCHEKMT2AMGLL | |
| Hydrochloric Acid SCHEMBL7366186 | 0.71 | LTA4H (0.47) | LTA4HBCHEHRH3HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625981-A1 | AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | claimed |
| WO-1993015080-A1 | AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |