Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 5/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | LAP3 | P28838 | 6/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362077 | 1.00 | SLC7A5 (0.42) | SLC7A5ANPEPDNPEPSLC1A3SLC1A2 | |
| SCHEMBL10163720 | 0.80 | SLC1A3 (0.32) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL18774945 | 0.77 | TSHR (0.38) | SLC7A5ANPEPDNPEPSLC1A3SLC1A2 | |
| SCHEMBL18774942 | 0.77 | TSHR (0.38) | SLC7A5ANPEPDNPEPSLC1A3SLC1A2 | |
| SCHEMBL891958 | 0.75 | RNPEP (0.38) | SLC7A5ANPEPSLC1A3SLC1A2LAP3 | |
| Hydrochloric Acid SCHEMBL8054309 | 0.75 | TSHR (0.36) | SLC7A5ANPEPDNPEPLAP3ERAP1 | |
| SCHEMBL8056306 | 0.74 | SLC7A5 (0.36) | SLC7A5 | |
| SCHEMBL18228767 | 0.74 | SLC7A5 (0.36) | SLC7A5 | |
| SCHEMBL10355433 | 0.73 | ANPEP (0.35) | SLC7A5ANPEPDNPEPLAP3ERAP1 | |
| SCHEMBL10354928 | 0.73 | ANPEP (0.35) | SLC7A5ANPEPDNPEPLAP3ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389535-A1 | RENIN INHIBITORS, PROCESSES FOR PREPARING THEM, METHODS FOR USING THEM, AND COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY (US) | 1990-10-03 | — | — | EP | disclosed |
| WO-1989007610-A1 | RENIN INHIBITORS CONTAINING alpha-HETEROATOM AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 1989-08-24 | — | — | WO | disclosed |
| WO-1989003841-A1 | RENIN INHIBITORS, PROCESSES FOR PREPARING THEM, METHODS FOR USING THEM, AND COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY (US) | 1989-05-05 | — | — | WO | disclosed |
| WO-1989003820-A1 | BRANCHED BACKBONE RENIN INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1989-05-05 | — | — | WO | disclosed |