Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10354928 | 1.00 | ANPEP (0.35) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL18774945 | 0.77 | TSHR (0.38) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL18774942 | 0.77 | TSHR (0.38) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| Hydrochloric Acid SCHEMBL8054309 | 0.75 | TSHR (0.36) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL2953547 | 0.74 | TSHR (0.39) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL7362079 | 0.73 | SLC7A5 (0.42) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL7362077 | 0.73 | SLC7A5 (0.42) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL7337830 | 0.72 | ANPEP (0.33) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL10695575 | 0.72 | ANPEP (0.37) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL7270284 | 0.71 | ANPEP (0.33) | ANPEPDNPEPSLC7A5ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218688-B1 | DIHALO-STATINE SUBSTITUTED RENIN INHIBITORS | THE UPJOHN COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4882420-A | HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS | THE UPJOHN COMPANY (US) | 1989-11-21 | — | — | US | disclosed |