Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4383380 | 0.87 | HSD17B10 (0.76) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL30206549 | 0.86 | KDM4E (0.75) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL9987671 | 0.86 | KDM4E (0.75) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL596065 | 0.84 | KDM4E (0.72) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL5052466 | 0.84 | KDM4E (0.72) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL7365515 | 0.83 | KDM4E (0.71) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL23682791 | 0.83 | KDM4E (0.81) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL12781875 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL15007834 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL15630682 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100543032-C | Streptogramin derivatives, preparation method and compositions containing them | AVETIS PHARMA S A (FR) | 2009-09-23 | — | — | CN | disclosed |
| CN-1961878-A | Streptogramin derivatives, their preparation and compositions containing them | AVENTIS PHARMA SA (FR) | 2007-05-16 | — | — | CN | disclosed |
| CN-1358194-A | Streptogramin derivatives, preparation method and compositions containing them | AVETIS PHARMA S A (FR) | 2002-07-10 | — | — | CN | disclosed |
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |