Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.75 |
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206549 | 1.00 | KDM4E (0.75) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL7362098 | 0.86 | KDM4E (1.00) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL5052466 | 0.84 | KDM4E (0.72) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL596065 | 0.84 | KDM4E (0.72) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL12781875 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL15630682 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL15007834 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL6387072 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| SCHEMBL14340860 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL4383380 | 0.81 | HSD17B10 (0.76) | KDM4EHSD17B10HPGDCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511215-B | Aryl piperazine/piperidine compound and application thereof | 复旦大学 | 2023-03-28 | — | — | CN | disclosed |
| US-8383631-B2 | 1,6-disubstituted-3-amino-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-C]pyridin-7-one compounds and preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-26 | — | — | US | disclosed |
| US-20110319619-A1 | NOVEL 1,6-DISUBSTITUTED-3-AMINO-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE COMPOUNDS AND PREPARATION THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319619-A1 | NOVEL 1,6-DISUBSTITUTED-3-AMINO-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE COMPOUNDS AND PREPARATION THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, THPO, PLEC | KDM4E 779/4885HSD17B10 4397/4885HPGD 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.