⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350655 | 0.88 | ATF4 (0.30) | — | |
| SCHEMBL2092407 | 0.86 | — | — | |
| SCHEMBL578660 | 0.85 | — | — | |
| SCHEMBL14814376 | 0.79 | — | — | |
| SCHEMBL6530662 | 0.77 | — | — | |
| SCHEMBL16141767 | 0.76 | — | — | |
| SCHEMBL12734368 | 0.76 | — | — | |
| SCHEMBL4967783 | 0.76 | — | — | |
| SCHEMBL19236347 | 0.76 | — | — | |
| SCHEMBL28197064 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190047966-A1 | NOVEL COMPOUND AND PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2019-02-14 | — | — | US | disclosed |
| EP-3409662-A1 | NOVEL COMPOUND AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Meiji Seika Pharma Co., Ltd. (JP) | 2018-12-05 | — | — | EP | disclosed |
| WO-2000012082-A1 | FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |