Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 11/20 | 0.52 |
| ▸ | ANPEP | P15144 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288013 | 0.86 | — | — | |
| SCHEMBL23391155 | 0.86 | — | — | |
| SCHEMBL562061 | 0.79 | GSR (0.46) | ENPEPANPEPS1PR2S1PR1ALDH1A1 | |
| SCHEMBL285212 | 0.79 | ENPEP (0.65) | ENPEPANPEPFOLH1S1PR2S1PR1 | |
| SCHEMBL28185762 | 0.79 | ENPEP (0.43) | ENPEPANPEPS1PR2S1PR1ALDH1A1 | |
| SCHEMBL159650 | 0.79 | GSR (0.46) | ENPEPANPEPS1PR2S1PR1ALDH1A1 | |
| SCHEMBL288689 | 0.79 | GSR (0.46) | ENPEPANPEPS1PR2S1PR1ALDH1A1 | |
| SCHEMBL289092 | 0.79 | ENPEP (0.65) | ENPEPANPEPFOLH1S1PR2S1PR1 | |
| SCHEMBL60354 | 0.79 | GSR (0.46) | ENPEPANPEPS1PR2S1PR1ALDH1A1 | |
| SCHEMBL6666416 | 0.78 | ENPEP (0.46) | ENPEPANPEPS1PR2S1PR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543425-A | ANTIAGGLOMERANTS | G. D. SEARLE & CO. (US) | 1996-08-06 | — | — | US | disclosed |
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |