Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.83 |
| ▸ | MMP1 | P03956 | 15/20 | 0.83 |
| ▸ | MMP9 | P14780 | 12/20 | 0.83 |
| ▸ | MMP3 | P08254 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922743 | 1.00 | MMP2 (0.83) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL8000523 | 0.91 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7504602 | 0.91 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7916917 | 0.81 | MMP2 (0.70) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7361102 | 0.81 | MMP2 (0.70) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7503389 | 0.81 | MMP2 (0.71) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7508422 | 0.81 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7998724 | 0.81 | MMP2 (0.81) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7924931 | 0.80 | MMP2 (0.83) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7924924 | 0.80 | MMP2 (0.83) | MMP2MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |