Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 10/20 | 0.80 |
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362452 | 1.00 | SERPINE1 (0.80) | SERPINE1PRF1GSK3BALDH1A1GAA | |
| SCHEMBL7358033 | 0.89 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7358028 | 0.89 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7353995 | 0.88 | SERPINE1 (1.00) | SERPINE1MAPTKMT2A | |
| SCHEMBL7363192 | 0.88 | SERPINE1 (0.82) | SERPINE1ALDH1A1GAAMAPTNPC1 | |
| SCHEMBL7363197 | 0.88 | SERPINE1 (0.82) | SERPINE1ALDH1A1GAAMAPTNPC1 | |
| SCHEMBL7359539 | 0.88 | SERPINE1 (0.82) | SERPINE1ALDH1A1MAPTKMT2A | |
| SCHEMBL7359534 | 0.88 | SERPINE1 (0.82) | SERPINE1ALDH1A1MAPTKMT2A | |
| SCHEMBL7353987 | 0.88 | SERPINE1 (1.00) | SERPINE1MAPTKMT2A | |
| SCHEMBL7359303 | 0.88 | SERPINE1 (1.00) | SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995032190-A2 | PHARMACEUTICAL DIKETOPIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-11-30 | — | — | WO | claimed |
| US-5750530-A | PLASMINOGEN ACTIVATOR INHIBITORS | XENOVA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| WO-1995032190-A2 | PHARMACEUTICAL DIKETOPIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-11-30 | — | — | WO | disclosed |