SCHEMBL7362474

SCHEMBL7362474

CCOC(COC)N(C(COC)OCC)C(COC)OCC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2966879 0.75
SCHEMBL13541655 0.69 THRB (0.42) THRBLMNA
SCHEMBL2332578 0.69 THRB (0.42) THRBLMNA
SCHEMBL5450674 0.69
SCHEMBL11423706 0.69 THRB (0.32) THRBLMNA
SCHEMBL1397073 0.67
SCHEMBL12842503 0.67
SCHEMBL9715124 0.65
SCHEMBL8672454 0.65 THRB (0.38) THRBLMNA
SCHEMBL1136403 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0892780-A1 M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1999-01-27 EP disclosed
WO-1997030971-A1 M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-28 WO disclosed
US-5290789-A Antipsychotically effective compounds STERLING WINTROP INC. (US) 1994-03-01 US disclosed